Meet Inspiring Speakers and Experts at our 3000+ Global Conference Series Events with over 1000+ Conferences, 1000+ Symposiums
and 1000+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business.

Explore and learn more about Conference Series : World's leading Event Organizer

Back

Michael S Kasparek

Michael S Kasparek

University of Munich, Germany

Title: Long-term quality of life of patients with permanent end ileostomy: Results of a nationwide cross-sectional survey

Biography

Biography: Michael S Kasparek

Abstract

Background: Patients with permanent end ileostomy are at high risk for detrimental stomal effects on their quality of life (QoL). However, there are little data regarding long-term QoL in these patients.

Objective: To assess long-term QoL in patients with permanent end ileostomy.

Data Sources and Study Selection: A cross-sectional survey of 1,434 patients with permanent end ileostomy registered at the German self-help organization, ILCO.

Main Outcome Measures: Assessment of QoL was performed according to the Short Form (SF-)36, including physical (PCS) and mental component summary (MCS) scores, Gastrointestinal Quality of Life Index (GIQLI), and the Cleveland Global Quality of Life Index (CGQLI). Multivariate risk factor analysis was performed.

Results: A total of 783 responders were included. The indications for ileostomy included ulcerative colitis (44%), Crohn’s disease (38%), and colorectal cancer (7%). Adverse effects in daily life due to stoma were reported by 72% of participants.  QoL was significantly impaired compared to the general population on all summary scores and several subscales (PCS: 44.6±10.4 (Mean±SD) vs. 50.2±10.2, P<0.001; MCS: 47.5±10.7 vs. 51.5±10.2, P<0.001; GIQLI: 94.4±16.4 vs. 126.0, P<0.001). Stoma care problems were reported by 63% of respondents to affect QoL, including parastomal hernia (P<0.001), stenosis (P=0.003), and prolapse (P=0.0078). Vitamin-B12, iron, and zinc deficiencies were also associated with diminished QoL, with vitamin-B12-deficiency particularly associated with reduced mental and emotional QoL. The profound negative effect of stoma care problems and deficiencies was confirmed by multivariate analysis.

Conclusions: QoL was markedly impaired in patients with permanent end ileostomy compared to the general population. The main reasons were stoma-associated morbidity and deficiency syndromes. These findings emphasize the importance of prevention, screening, and adequate treatment.

Speaker Presentations

Speaker PDFs

Speaker PPTs Click Here